Meciuri Sepsi OSK sezonul 2021-2022 in Liga1
| ETAPA | DATA | GAZDE | OASPETI | SCOR |
|---|---|---|---|---|
| 1 | 16 iul 2021 | Sepsi OSK | Academica Clinceni | 2-0 |
| 2 | 26 iul 2021 | FC Chindia Târgoviște | Sepsi OSK | 1-1 |
| 3 | 2 aug 2021 | Sepsi OSK | CS Mioveni | 1-2 |
| 4 | 9 aug 2021 | FCV Farul Constanța | Sepsi OSK | 1-0 |
| 5 | 15 aug 2021 | Sepsi OSK | FC Arges | 0-2 |
| 6 | 23 aug 2021 | FCSB | Sepsi OSK | 1-1 |
| 7 | 29 aug 2021 | Sepsi OSK | FC Botosani | 1-1 |
| 8 | 13 sep 2021 | Universitatea Craiova | Sepsi OSK | 1-1 |
| 9 | 19 sep 2021 | Sepsi OSK | UTA Arad | 0-0 |
| 10 | 27 sep 2021 | Gaz Metan Medias | Sepsi OSK | 0-0 |
| 11 | 2 oct 2021 | Sepsi OSK | Rapid București | 2-2 |
| 12 | 16 oct 2021 | Sepsi OSK | FC Voluntari | 1-2 |
| 13 | 25 oct 2021 | CFR Cluj | Sepsi OSK | 2-0 |
| 14 | 31 oct 2021 | Sepsi OSK | Dinamo București | 4-1 |
| 15 | 6 noi 2021 | FCU Craiova | Sepsi OSK | 1-1 |
| 16 | 19 noi 2021 | Academica Clinceni | Sepsi OSK | 0-2 |
| 17 | 27 noi 2021 | Sepsi OSK | FC Chindia Târgoviște | 0-0 |
| 18 | 5 dec 2021 | CS Mioveni | Sepsi OSK | 0-2 |
| 19 | 12 dec 2021 | Sepsi OSK | FCV Farul Constanța | 1-0 |
| 20 | 15 dec 2021 | FC Arges | Sepsi OSK | 1-1 |
| 21 | 19 dec 2021 | Sepsi OSK | FCSB | 0-0 |
| 22 | 24 ian 2022 | FC Botosani | Sepsi OSK | 1-0 |
| 23 | 28 ian 2022 | Sepsi OSK | Universitatea Craiova | 3-1 |
| 24 | 5 feb 2022 | UTA Arad | Sepsi OSK | 1-0 |
| 25 | 8 feb 2022 | Sepsi OSK | Gaz Metan Medias | 2-0 |
| 26 | 11 feb 2022 | Rapid București | Sepsi OSK | 1-1 |
| 27 | 19 feb 2022 | FC Voluntari | Sepsi OSK | 3-1 |
| 28 | 26 feb 2022 | Sepsi OSK | CFR Cluj | 0-2 |
| 29 | 1 mar 2022 | Dinamo București | Sepsi OSK | 1-3 |
| 30 | 4 mar 2022 | Sepsi OSK | FCU Craiova | 2-1 |
